Advancing Synthetic Bioactive Glass Osteobiologics Applications
Engineered to Activate Bone.
The first and only FDA-cleared synthetic 45S5 bioactive glass osteobiologic uniquely formulated to combine with DBM to amplify regenerative bone formation.
NanoFUSE forms a 3D ultra-porous calcium hydroxyapatite layer in as early as 24 hours — initiating a biologically active surface designed for bone integration.
WHY NANOFUSE
Bioactive by Design
Upon contact with aqueous body fluids, NanoFUSE begins ionic exchange that leads to rapid formation of a calcium hydroxyapatite (CHA) layer — the same mineral phase found in native bone.
Synthetic Precision
Manufactured 45S5 bioactive glass ensures consistency, reliability, and no donor site morbidity or disease transmission risk.
Amplifies DBM Performance
NanoFUSE is uniquely formulated to combine with demineralized bone matrix (DBM), enhancing scaffold architecture and supporting regenerative signaling.
THE SCIENCE SNAPSHOT
From Implantation to Integration
Surface activation upon fluid exposure
Formation of ultra-porous CHA layer (as early as 24 hours)
Osteoblast attachment and proliferation
Progressive remodeling into native bone
NanoFUSE transforms from a synthetic ceramic into a biologically active regenerative interface.
CLINICAL APPLICATIONS
Designed for use in:
Spine
Orthopedics
Foot & ankle
Fills bone voids
Built for surgeons seeking scientifically proven synthetic bioactive regeneration.
A NEW STANDARD IN SYNTHETIC OSTEOBIOLOGICS
NanoFUSE Biologics activates DBM biology for a robust effectiveness.
By combining nanostructured bioactive glass with DBM compatibility, NanoFUSE represents a shift toward intelligent regenerative materials engineered for early surface activation and predictable performance.